Now accepting US patients · Free 15-minute consultation · Direct flights to San Diego, 20 minutes from the border
We Believe You

If you have been told
it is in your head — read this.

After years of doctors, protocols, and being told nothing is wrong — Santa Maria is where serious science, modern medicine, and the human spirit work together.

Book a Free 15-min Consultation +1 866-890-5574

Or message us on WhatsApp · Most patients hear back within 30 minutes

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★★★★★ 4.7 on Google · 82 verified reviews
8,500+ on Instagram
TICKPLEX Diagnostic Partner
60+ Donor Markers Verified
2,000+ Facebook community
Live Blood Microscopy · Fewer than 10 doctors worldwide
Patient stories on YouTube
★★★★★ 4.7 on Google · 82 verified reviews
8,500+ on Instagram
TICKPLEX Diagnostic Partner
60+ Donor Markers Verified
2,000+ Facebook community
Live Blood Microscopy · Fewer than 10 doctors worldwide
Patient stories on YouTube
You Did Not Imagine It

Most chronic Lyme patients arrive at Santa Maria the same way.

First come the years of misdiagnosis — the lab work that always comes back "normal," the suspicion in the clinician's voice, the side-eye from family who quietly stopped believing.

Then come the tens of thousands of dollars spent on protocols that did not work — supplements, IVs, restrictive diets, unproven treatments, second and third and fourth opinions.

And then, eventually, you arrive somewhere new still in pain, still exhausted, still looking for someone who will actually sit down, listen, and believe what you are telling them about your own body.

Santa Maria is where patients come when the usual answers ran out.

We see you. We were you. And we built Santa Maria for you.

— Mariya Kurilina, Founder

Four Pillars Of Care

How we actually treat the patient — not just the test result.

01 — Diagnose

Find what was missed.

Comprehensive panels, Live Blood Microscopy, TICKPLEX, methylation, mycotoxin, and viral reactivation testing.

02 — Detoxify

Clear the load.

IV protocols, ozone, infrared sauna, lymphatic, ionic detox — sequenced for chronically toxic patients.

03 — Regenerate

Rebuild the system.

In-house stem cell and exosome therapy, peptides, NAD+, and mitochondrial support.

04 — Sustain

Continuity of care.

30 and 90-day follow-up labs, written continuity-of-care plans, and direct access to your medical team.

Why Santa Maria

Doctor-led integrative care. Not alternative. Not corporate.

The Santa Maria Method

A protocol built from the patient seat.

Founder Mariya Kurilina developed this approach after her own multi-year battle with Lyme disease and chronic viral infections. Refined alongside physicians, scientists, and biologists — built for the patients the system had given up on.

Founder · Mariya Kurilina
Diagnostic Depth

Lab work the U.S. system simply does not offer.

Live Blood Microscopy practiced by fewer than 10 doctors worldwide. TICKPLEX partnership for next-generation tick-borne diagnostics. Methylation and mycotoxin panels read by clinicians who know what they're looking at.

Stem Cell Quality
60+

Donor markers verified per batch. Pathogen-free quality assurance. Niche pre-conditioning protocol developed in-house — not the off-the-shelf product offered elsewhere.

Scientific Co-Founder
h-53

Dr. Yuri Nikolsky — molecular biologist, geneticist, h-index 53, 200+ publications. Professor at the University of Sharjah. The science behind the method.

What Patients Are Experiencing

Specific. Measurable. Documented.

0years
Average biological age reduction across program completers
00%
Decrease in blood sugar, cholesterol, and triglycerides
00%
Improvement of renal function in monitored patients
Confirmed
Microscopy-verified blood detoxification, observed pre & post-program
What Patients Say

4.7 on Google. 82 verified reviews.

★★★★★ Verified by Google · Real patient reviews
★★★★★

"They actually listened. After years of being told it was anxiety, someone finally ran the right tests and treated me like a human being."

— Verified Google Review

★★★★★

"The diagnostics were on a different level. The protocol was personalized. The team was world-class. This place changed my life."

— Verified Google Review

Health Programs

Choose the depth that fits your case.

The People Behind The Work

A clinic built by patients, for patients.

Mariya Kurilina
Founder · Patient · Practitioner

"After my own years of being dismissed by the medical system, I built the clinic I needed and could not find. Santa Maria is where patients are believed first."

Dr. Yuri Nikolsky
Scientific Co-Founder · Molecular Biologist

Molecular biologist and geneticist with an h-index of 53. Professor at the University of Sharjah. Author of over 200 peer-reviewed publications in molecular biology, systems pharmacology, and translational medicine.

How It Works

From first call to first day of treatment.

Step 01
Free 15-minute consultation call
Step 02
Personalized treatment plan
Step 03
Travel to Rosarito — 20 minutes from the border
Step 04
Begin your program in our oceanfront retreat
Common Questions

What patients ask before they come.

Don't see your question? Book a free 15-minute call and we'll answer everything in plain English.

Programs run from 3 to 14 days, depending on the depth of your case. The 3-Day Intensive is diagnostic-focused; the 14-Day Restoration is built for multi-system chronic illness. We help you choose during your free consultation.
We are at Libre Tijuana–Ensenada KM.52, Calle Pescadores 823, El Campito, Playas de Rosarito — about 40 miles south of San Diego and roughly 20 minutes from the border. Most US patients fly into San Diego (SAN); we coordinate ground transportation from the airport directly to the clinic.
Chronic Lyme disease and tick-borne co-infections, mold and biotoxin illness, chronic viral reactivation (EBV, HHV-6, CMV), long COVID, autoimmune presentations, and complex multi-system chronic illness that has been under-served by conventional care.
Direct access, no insurance gatekeepers. Programs are cash-pay so we can give you the time and depth your case requires.
Mornings begin with diagnostics or scheduled therapeutics — IV protocols, ozone, peptide therapy, hyperbaric, or stem cell sessions depending on your plan. Afternoons combine recovery modalities like infrared sauna, lymphatic work, and physician check-ins. Evenings are for rest, oceanfront walks, and clinical observation.
You leave with a written continuity-of-care plan, follow-up labs scheduled, and direct access to our medical team. Most patients have a 30-day and 90-day touchpoint, and many return for maintenance programs as needed.
Your Next Step

If you are ready to be heard,
we are ready to listen.

Book Your Free Consultation +1 866-890-5574 Or message us on WhatsApp · Mon–Sat, 9am–6pm Pacific
Book Free Consultation